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Registros recuperados: 5
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A first evaluation on the use of Ardea albus feathers as bioindicators of mercury burden in Amazonian ecosystems Acta Amazonica
Gomes,Andreza Lourdes; Vieira,José Luiz Fernandes; Pinheiro,Maria da Conceição Nascimento; Marceliano,Maria Luiza Videira.
We evaluated in this study the total mercury concentration in feathers of Ardea albus collected in a colony located in the city of Belem-PA, Brazil in a prospective trial for its use as bioindicators of mercury burden in Amazonia ecosystems. An Atomic absorption spectrophotometry with gold amalgamation was used for the metal determination. The total mercury average concentration in body feathers was 2.2 ± 1.5 µg.g-1 and 1.3 ± 0.9 µg.g-1 in wing feathers. No correlation was observed between total mercury concentration and the length of body or wing feathers. Total mercury concentration was above 5 µg.g-1 dry weight in only one body feather sample.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mercury; Ardea albus; Birds; Feathers; Environmental.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000400025
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Concentrations of rifampicin in pre-dose samples in patients with pulmonary tuberculosis BJID
Uchoa,Breno Kristoffer Beleza; Albério,Carlos Augusto Abreu; Pinto,Ana Carla Godinho; Lucena,Stefania de Medeiros Araujo; Vieira,José Luiz Fernandes.
ABSTRACT Rifampicin is used in both phases of treatment for tuberculosis. In chronic use, the short half-life and the self-induction of metabolism can decrease the levels of the drug below the minimal inhibitory concentration. The aim of the study was to investigate whether plasma concentrations of rifampicin are sustained above 0.5 µg/mL in patients with tuberculosis using 600 mg/day. Rifampicin was measured in plasma by high-performance liquid chromatography and a sputum smear microscopy was performed in all days of the study. A total of 44 male patients completed the study. On days 31, 61 and 91, the mean plasma concentrations of rifampicin were 0.6 (0.5) µg/mL, 0.55 (0.5) µg/mL and 0.46 (0.4) µg/mL. There was a high variation of rifampicin levels...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Infectious disease; Tuberculosis; Rifampicin.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000200130
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Natural gaps associated with oxidative stress in Willisornis poecilinotus (Aves: Thamnophilidae) in a tropical forest Acta Amazonica
Gomes,Andreza de Lourdes Souza; Gonçalves,Andrey Felipe Gomes; Vieira,José Luiz Fernandes; Marceliano,Maria Luiza Videiro; Silva,José Maria Cardoso da.
Natural disturbances in tropical forests modify the availability and quality of resources and alter the patterns of bird distribution. These environmental changes increase the metabolic rate and disrupt the redox balance promoting oxidative stress. This study aimed to compare the abundance of Willisornis poecilinotus between gaps and the understory of a forest with undisturbed canopy at Caxiuanã National Forest. The abundance was correlated with vegetation heights. The oxidative stress and the stress promoting factors were determined in both sites of sampling. We captured 81 specimens of W. poecilinotus. The number of captures was high in gaps. The specimens sampled at gaps showed high levels of oxidative stress. The biomarkers of oxidative stress were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidants; Environmental disturbances; Redox balance; Lipid peroxidation.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672014000200006
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Patient age does not affect mefloquine concentrations in erythrocytes and plasma during the acute phase of falciparum malaria BJID
Vieira,José Luiz Fernandes; Borges,Larissa Maria Guimarães; Ferreira,Michelle Valéria Dias; Rivera,Juan Gonzalo Bardarez; Gomes,Margarete do Socorro Mendonça.
Abstract Objective To evaluate whether patient age has a significant impact on mefloquine concentrations in the plasma and erythrocytes over the course of treatment for uncomplicated falciparum malaria. Methods A total of 20 children aged between 8 and 11 years and 20 adult males aged between 22 and 41 years with uncomplicated falciparum malaria were enrolled in the study. Mefloquine was administered to patients in both age groups at a dose of 20 mg kg−1. The steady-state drug concentrations were measured by reversed-phase high performance liquid chromatography. Results All patients had an undetectable mefloquine concentration on day 0. In adults, the plasma mefloquine concentrations ranged from 770 to 2930 ng mL−1 and the erythrocyte concentrations...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Malaria; Infectious disease; Parasitology; Mefloquine.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500482
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Quinine levels in patients with uncomplicated falciparum malaria in the Amazon region of Brazil BJID
Vieira,José Luiz Fernandes; Borges,Larissa Maria Guimarães; Nascimento,Margareth Tavares Silva; Gomes,Andreza de L.S..
We examined the plasmatic concentrations of quinine in patients with uncomplicated falciparum malaria in an endemic area of the Amazon region in Brazil in a prospective clinical trial, in which a standard three-day course of oral quinine plus doxycycline was used. We measured the quinine in the plasma samples on days 0 and 3by high performance liquid chromatography. The mean concentration of quinine was 6.04 ±2.21 µg/mL in male patients and 5.98 ±1.95 µg/mL in female patients. No significant differences in quinine concentration were observed between these two groups. All samples collected before starting treatment were negative for quinine. This information could help in the development of strategies for the rational use of antimalarial drugs in Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Falciparum malaria; Quinine; Treatment.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500001
Registros recuperados: 5
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